Preheat oven to 425℉. Line a large rimmed baking sheet with parchment paper.
Place the tortillas onto the pan. Use 1/3 cup of ground chicken on each tortilla and flatten the chicken out thinly and evenly. Sprinkle with salt, garlic powder, onion powder and Italian herb blend generously. Bake for 10 minutes. Remove from oven and spread on the marinara sauce, sprinkle with mozzarella, pesto, pepperoni and lastly with parmesan. Bake again for 10-12 minutes. Sprinkle with chili pepper flakes, fold them into tacos and enjoy!